Home Chemistry Heterocyclic Building Blocks Pyridines Thiazolo[5,4-B]Pyridine
Substitution Reactions: Thiazolo[5,4-b]pyridine can undergo nucleophilic substitution reactions, where an atom or group on the molecule is replaced by a nucleophile. For example, if the nitrogen or sulfur atom is attached to a leaving group, it can be replaced by a nucleophile.
Acylation and Alkylation Reactions: Thiazolo[5,4-b]pyridine can react with acylating agents (like acyl chlorides) or alkylating agents (like alkyl halides) to form acyl or alkyl derivatives.
Cyclization Reactions: Depending on the functional groups present, thiazolo[5,4-b]pyridine can undergo intramolecular cyclization reactions to form fused ring systems or other cyclic compounds.
Metal Complexation: Thiazolo[5,4-b]pyridine can coordinate with metal ions to form metal complexes. This is especially relevant if there are electron-rich sites on the molecule that can act as ligands.
Condensation Reactions: Thiazolo[5,4-b]pyridine can participate in condensation reactions with suitable reagents to form larger molecules.
Aromatic Substitution: If there are substituents on the aromatic ring, thiazolo[5,4-b]pyridine can undergo various types of aromatic substitution reactions, such as electrophilic aromatic substitution.
Heterocyclic Chemistry: Thiazolo[5,4-b]pyridine can participate in reactions typical of heterocyclic compounds, such as reactions with other heteroatoms (e.g., oxygen, nitrogen) to form fused heterocycles.
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Ethyl 5-chlorothiazolo[5,4-b]pyridine-2-carboxylate
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5-Chloro-2-methylthiazolo[5,4-b]pyridine
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5-Bromo-2-chlorothiazolo[5,4-b]pyridine
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